The Key Role of Akkermansia in a Maintaining a Healthy Gut and Weight

Dr. Erin Hendriks • June 4, 2023

The Key Role of Akkermansia in a Maintaining a Healthy Gut and Weight

The gut is home to trillions of microbes that play crucial roles in various bodily functions, including digestion, immune function, and metabolism. Despite being a relatively new discovery, Akkermansia has emerged as a powerful player that holds the key to maintaining a healthy gut and achieving sustainable weight loss.


Akkermansia and Gut Health

A healthy gut is one that maintains a balance between beneficial and harmful microbes, and Akkermansia plays a pivotal role in achieving this. Akkermansia helps to maintain a healthy gut lining, reducing the risks of gut inflammation, gut permeability, and other gut dysfunctions.


Akkermansia and Metabolic Health

Akkermansia has also been linked to numerous metabolic benefits, including weight loss and reduced inflammation. Studies have shown that people with obesity tend to have lower levels of Akkermansia than those with normal weight. 


The anti-inflammatory properties of Akkermansia also make it a powerful ally in metabolic health. Inflammatory substances in the body can interfere with metabolic processes, leading to insulin resistance and weight gain. By reducing inflammation, Akkermansia promotes optimal metabolic health, helping people achieve healthy and sustainable weight loss.


Ways to Boost Akkermansia Levels

Dietary modifications involve cutting down on processed foods, sugar, and trans fats, and consuming food rich in fiber, polyphenols, and other nutrients. Such foods nourish the beneficial gut bacteria, including Akkermansia.


Exercise has also been found to increase Akkermansia levels and improve gut and metabolic health. 


Involve a Functional Medicine Practitioner

As beneficial as Akkermansia may be, it's important to remember that gut health and metabolic health are complex and multifaceted. Achieving optimal health requires a comprehensive approach that involves multiple interventions, including dietary and lifestyle modifications, nutraceutical supplementation, and if necessary, medication.


As such, it's important to involve a functional medicine physician who can develop personalized treatment plans that address your unique health needs. Functional medicine physicians are trained to treat the root cause of health imbalances, rather than merely managing symptoms, and can help you achieve optimal health through a holistic approach.

*AI Disclosure: This content may contain sections generated with AI with the purpose of providing you with condensed helpful and relevant content, however all personal opinions are 100% human made as well as the blog post structure, outline and key takeaways.

* Affiliate Disclosure: Some of the links on www.elle-md.com may contain affiliate links meaning that we will get a commission for recommending products at no extra cost to you.

*Blog Disclaimer: Please note that reading our blog does not replace any health or medical advice consultation. Read our blog disclaimer here.

Meet the Drs.

Dr. Hendriks and Dr. Castillo MacKenzie are board-certified physicians, female, specialized, with over 10 years of experience.


Elle MD started after practicing in a traditional primary care setting together for over a decade. We grew frustrated with the current healthcare model, which places no emphasis on addressing the root cause of chronic disease. A lot of times, conventional care doesn’t even promote overall wellness! 


We founded Elle MD in Royal Oak, MI, with a vision of providing this care in a compassionate and personalized way. 

WEIGHT MANAGEMENT FUNCTIONAL MEDICINE BOOK AN APPOINTMENT

Download your free guide

FREE GUIDE
September 12, 2025
Struggling with thyroid symptoms and not sure where to turn? Learn what doctor specializes in thyroid care and how to find the right support near you.
September 12, 2025
Struggling with low energy, brain fog, or weight changes? Discover the best thyroid supplements for women, plus which ones to avoid according to a hormone expert.
September 6, 2025
Struggling with bloating, fatigue, or mood swings? Discover 15 clear signs of an unhealthy gut and how Elle MD can help restore balance.
September 4, 2025
Wondering what is the best gut health supplement? Discover doctor-approved vitamins, top supplements, and the real path to healing your gut from the inside out.
August 1, 2025
As we age, changes in our skin can feel sudden and confusing—thinner texture, more dryness, loss of elasticity, and that “tired” look that shows up even after a good night’s sleep. These are natural changes, but they don’t have to be inevitable. In this post, we’re addressing some of the most common questions we get about aging skin, the role of estrogen, and how we integrate evidence-based solutions—like topical hormones and therapeutic skincare—to help restore skin vitality from the inside out. Why does skin change so much with age? Collagen loss starts in our 30s and accelerates during menopause, driven largely by hormonal shifts—especially the decline in estrogen. Estrogen supports hydration, elasticity, and collagen production, so when it drops, the skin becomes drier, thinner, and more fragile. You may also notice increased sensitivity, slower healing, and a duller appearance. What role does estrogen play in skin health? Estrogen isn’t just a reproductive hormone—it plays a critical role in skin physiology. It improves: Collagen production Skin thickness Moisture retention Wound healing Sebum (natural oil) production For some women, topical estrogen can be a safe, localized way to target skin aging—especially in areas like the face, neck, and even vaginal tissue, where estrogen receptors are abundant. We often use compounded low-dose topical estriol or estradiol as part of a customized plan. It’s not about reversing the clock—it’s about optimizing how your skin functions now. Are topical hormones safe? When prescribed appropriately and monitored, topical estrogen for skin use is generally well-tolerated and low-risk. Unlike systemic hormone therapy, these formulations are localized and often used at low doses. We assess your history and current hormone levels before initiating any protocol and monitor your response over time. What else helps aging skin? This is where skincare gets smarter. We look at: Barrier repair: A compromised skin barrier leads to sensitivity, dryness, and inflammation. Inflammation control: Chronic low-level inflammation accelerates aging. Antioxidant support: To neutralize daily oxidative damage. This is why we’re now offering Epionce® in our practice. It’s a dermatologist-developed line that aligns well with a functional approach—focused on skin barrier health, calming inflammation, and restoring a more resilient skin environment. We love it because it’s evidence-based, botanical-forward, and works beautifully alongside hormonal support or other medical treatments.  Where do I start if I’m noticing aging changes? Start with a comprehensive evaluation: hormones, nutrition, stress, and skin history all matter. For some, that means testing estrogen levels and considering topical support. For others, it means addressing gut health, reducing inflammatory load, or rethinking skincare ingredients. We’re here to help you understand what’s changing—and offer personalized tools to help your skin reflect how good you’re starting to feel inside. Aging skin is not just a cosmetic issue—it’s a reflection of internal changes, especially hormone shifts. With thoughtful, integrative care—including hormone support when appropriate and smart topical therapies like Epionce—we can help restore balance and vitality at the cellular level.
July 5, 2025
Is hormone therapy safe for weight loss? Learn the risks, benefits, and how functional medicine helps women lose weight safely and naturally.
July 5, 2025
Struggling with stubborn weight gain? Learn how hormone therapy affects metabolism, when it can help with weight loss, and how functional medicine restores balance naturally.
July 5, 2025
Looking for the best weight loss supplements for women? Learn which vitamins, minerals, and natural supplements support metabolism, fat loss, and hormone balance.
July 5, 2025
Wondering who can prescribe weight loss medication? Learn whether you need a primary care doctor, endocrinologist, or weight loss specialist—and what options are available.
July 5, 2025
Not sure what type of doctor to see for weight loss? Learn the difference between weight loss specialists, functional medicine doctors, and medical weight loss clinics in Michigan.