How Diet Affects Your Body's Acid-Base Balance: The Hidden Impact of Inflammatory Foods

Dr. Erin Hendriks • March 20, 2025

The food we eat provides more than energy—it also influences our body's acid-base balance, which plays a crucial role in overall health

Many people don't realize that proinflammatory diets can increase the body's net acid load, leading to long-term health consequences. On the other hand, anti-inflammatory diets help maintain a healthier balance, reducing the risk of chronic diseases.


What Is a Diet-Dependent Net Acid Load?

Every food we consume, once digested, releases either an acidic or alkaline byproduct. This process contributes to what is known as diet-dependent net acid load (NEAL). A higher net acid load can lead to chronic low-grade metabolic acidosis, which has been linked to several health concerns, including:

  • Bone loss and increased risk of osteoporosis
  • Muscle breakdown and weakness
  • Kidney dysfunction
  • Increased systemic inflammation contributing to diseases like hypertension and cardiovascular conditions


The Role of Pro-inflammatory Diets in Metabolic Acidosis

Pro-inflammatory diets—such as the Western diet, high in processed foods, refined grains, and excess sodium—can significantly increase net acid load. Sodium chloride (table salt), commonly found in fast foods and processed snacks, is a major contributor to this imbalance. A high-sodium diet disrupts the body's natural acid-base regulation, contributing to an acidic internal environment that can accelerate aging, inflammation, and chronic disease progression.


Additionally, processed meats, refined sugars, and artificial additives often found in these diets increase acidity, adding stress to the kidneys, bones, and muscles over time.


Why Anti-Inflammatory Diets Are Beneficial

In contrast, anti-inflammatory diets help neutralize acidity and support overall health. These diets emphasize whole, plant-based foods with a lower net acid load, reducing the risk of metabolic acidosis. Legumes, leafy greens, fruits, and nuts are particularly beneficial because they have a neutral or alkaline effect on the body.


Legumes, for example, produce a near-zero net acid value, meaning they do not contribute to excess acidity in the body. Consuming more of these alkaline-forming foods can:

  • Improve bone health by preventing calcium loss
  • Support muscle preservation and reduce the risk of age-related muscle decline
  • Enhance kidney function by reducing the burden of acid excretion
  • Decrease systemic inflammation, lowering the risk of heart disease, diabetes, and other chronic conditions


Nutrition for Optimal Health

If you want to reduce inflammation and maintain a healthier acid-base balance, consider making the following dietary adjustments:


✅ Increase alkaline-forming foods:

  • Leafy greens (spinach, kale, arugula)
  • Fresh fruits (bananas, oranges, berries)
  • Nuts and seeds (almonds, flaxseeds, chia seeds)
  • Legumes (lentils, chickpeas, black beans)


❌ Reduce acid-forming foods:

  • Processed meats (hot dogs, bacon, deli meats)
  • Refined grains (white bread, pasta, sugary cereals)
  • High-sodium processed foods (fast food, canned soups, packaged snacks)
  • Artificial sweeteners and additives


By prioritizing whole, nutrient-dense foods and limiting processed, high-sodium options, you can help shift your body's acid-base balance toward a healthier, more alkaline state. This simple change can profoundly impact your bone strength, muscle health, kidney function, and overall inflammation levels.


Final Thoughts

Your diet is critical in maintaining a balanced internal environment. While pro-inflammatory diets contribute to an acidic, inflammatory state promoting chronic disease, anti-inflammatory diets help neutralize acidity and support long-term well-being. Making conscious food choices can help your body function optimally and reduce the risk of metabolic disorders, cardiovascular disease, and age-related decline.


Start incorporating more alkaline-forming foods today and experience the benefits of an anti-inflammatory lifestyle!


References: 

  1. Scheiber A, Mank V. Anti-Inflammatory Diets. [Updated 2023 Oct 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
  2. Zhang L, Curhan GC, Forman JP. Diet-dependent net acid load and risk of incident hypertension in United States women. Hypertension. 2009 Oct;54(4):751-5. doi: 10.1161/HYPERTENSIONAHA.109.135582. Epub 2009 Aug 10. PMID: 19667248; PMCID: PMC2777672.


*AI Disclosure: This content may contain sections generated with AI with the purpose of providing you with condensed helpful and relevant content, however all personal opinions are 100% human made as well as the blog post structure, outline and key takeaways.

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Meet the Drs.

Dr. Hendriks and Dr. Castillo MacKenzie are board-certified physicians, female, specialized, with over 10 years of experience.


Elle MD started after practicing in a traditional primary care setting together for over a decade. We grew frustrated with the current healthcare model, which places no emphasis on addressing the root cause of chronic disease. A lot of times, conventional care doesn’t even promote overall wellness! 


We founded Elle MD in Royal Oak, MI, with a vision of providing this care in a compassionate and personalized way. 

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